Access Denied when uploading to Arduino Nano

Hi, first post, I'm glad I finally found this solution, three days wasted after buying a genuine Arduino Nano, and yes it has an FTDI VCP chip.
The Serial Monitor was the issue, I have not used the Serial Plotter.
Windows 10, fully updated. Arduino IDE 2.1.0. now waiting for IDE update
Cheers (at last)
Fred