The document discusses an innovative approach named memetic search in differential evolution (MSDE) aimed at improving the performance of the differential evolution (DE) algorithm, which is known for optimizing nonlinear problems but can suffer from premature convergence. By incorporating a memetic search strategy, the proposed MSDE demonstrates enhanced efficiency and effectiveness when tested against both benchmark and real-world optimization problems. Experimental results highlight that MSDE outperforms traditional DE and its recent variations in various optimization scenarios.