This paper presents a methodology for the optimal placement and sizing of multiple distributed generators (DG) in primary distribution networks to minimize power losses. The analysis compares two methods: the loss sensitivity factor (LSF) and the iterative algorithm (IA), tested on 33-bus and 69-bus radial distribution systems, revealing that LSF achieves similar loss reductions with smaller DG sizes than IA. The findings emphasize the importance of optimal DG allocation in enhancing system efficiency and reducing power losses.